Gamma Hydroxybutyrate Effects

Gamma Hydroxybutyrate Effects Gamma Butyrolactone Uses

Gamma Butyrolactone (GBL)

Gamma butyrolactone (GBL) is a chemical in cleaning solutions and nail polish. In the body, GBL is converted to gamma-hydroxybutyrate (GHB), a date-rape drug. When the body converts GBL into GHB, it can turn off some functions of the nervous system. Despite serious safety concerns, people use GBL as a party drug, for athletic performance, depression, and other purposes, but there is no good scientific evidence to support these uses.

GBL is classified as a Schedule I controlled substance, making it illegal in the US. Don’t confuse GBL with Gamma-hydroxybutyrate (GHB) or 1,4-Butanediol. These chemicals are related but are not the same.

gamma butyrolactone


Insufficient Evidence to Rate Effectiveness for...

  • Causing relaxation.
  • Increasing mental clarity.
  • Relieving depression and stress.
  • Prolonging life.
  • Improving sexual performance and pleasure.
  • Reducing fat.
  • Releasing growth hormone.
  • Improving athletic performance.
  • Improving sleep.
  • As a body-builder or muscle-builder.
  • As a recreational drug.


Use of GBL, or the closely related gamma hydroxybutyrate (GHB) and butanediol (BD), has been linked to deaths and cases of serious side effects. These serious side effects include the inability to control the bowels, vomiting, mental changes, sedation, agitation, combativeness, memory loss, serious breathing and heart problems, fainting, seizures, coma, and death. The effects can be made worse by alcohol or narcotics such as morphine, heroin, and others. Long-term use may lead to withdrawal symptoms including insomnia, tremor, and anxiety.

Gamma Hydroxybutyrate (GHB)

gamma-Hydroxybutyric acid (or γ-hydroxybutyric acid (GHB), also known as 4-hydroxybutanoic acid) is a naturally occurring neurotransmitter and a depressant drug. It is a precursor to GABA, glutamate, and glycine in certain brain areas. It acts on the GHB receptor and is a weak agonist at the GABAB receptor. GHB has been used in the medical setting as a general anesthetic and as treatment for cataplexy, narcolepsy, and alcoholism.

It is also used illegally as an intoxicant, as an athletic-performance enhancer, as a date-rape drug, and as a recreational drug. It is commonly used in the form of a salt, such as sodium γ-hydroxybutyrate (NaGHB, sodium oxybate, or Xyrem) or potassium γ-hydroxybutyrate (KGHB, potassium oxybate). GHB is also produced as a result of fermentation, and is found in small quantities in some beers and wines, beef, and small citrus fruits.Succinic semialdehyde dehydrogenase deficiency is a disease that causes GHB to accumulate in the blood.

Gamma Hydroxybutyric


Possibly Effective for…

  • Treatment of loss of muscle control and weakness associated with a condition called narcolepsy. Taking GHB seems to help people with narcolepsy sleep at night so they are less likely to feel sleepy during the day. GHB also seems to help reduce the temporary paralysis that sometimes goes along with narcolepsy.
  • Pain, fatigue, and sleep problems associated with a condition called fibromyalgia.
  • Alcohol dependence and withdrawal.
  • Suppressing symptoms of withdrawal from heroin, opium, morphine, and other opiate drugs.

Insufficient Evidence to Rate Effectiveness for…

  • Reducing weight.
  • Enhancing muscle growth.
  • Causing sexual arousal.
  • Reducing pressure in the brain caused by head injury.
  • Other conditions.

Gamma Hydroxybutyrate Effects

The prescription medication gamma hydroxybutyrate (sodium oxybate) is POSSIBLY SAFE for adults who are taking it under close medical supervision for symptoms of a condition called narcolepsy.

Gamma hydroxybutyrate (GHB) is UNSAFE and illegal for use as a dietary supplement. Use of GHB, or the closely related gamma butyrolactone (GBL) and butanediol (BD), has been linked to at least three deaths and 122 cases of serious side effects. GHB can cause many serious side effects including headaches, hallucinations, dizziness, confusion, nausea, vomiting, drowsiness, agitation, diarrhea, sexual arousal, numbing of legs, vision problems, tightness of chest, mental changes, combativeness, memory loss, serious breathing and heart problems, seizures, coma, and death. GHB can be addictive. Long-term use may lead to withdrawal symptoms that are serious enough to require hospitalization.

Differences Between Gamma Butyrolactone (GBL) & Gamma Hydroxybutyrate (GHB)

Gamma butyrolactone (GBL) and gamma hydroxybutyrate (GHB) are both gamma hydroxybutyrate compounds that have similar chemical structures and can produce similar effects when consumed. However, there are some key differences between the two substances that are important to understand.

First, let’s take a closer look at the chemical structures of GBL and GHB. GBL is a lactone, which means it contains a cyclic ester group. It has the chemical formula C4H6O2 and is a clear, colorless liquid with a sweet, fruity odor. GHB, on the other hand, is a carboxylate and contains a carboxyl group. It has the chemical formula C4H8O3 and is also a clear, colorless liquid with a slightly salty or soapy taste.

One of the main differences between GBL and GHB is their legal status. In many countries, including the United States, GBL is a controlled substance and is illegal to possess, sell, or manufacture. GHB, on the other hand, is a Schedule I controlled substance in the United States, meaning it has a high potential for abuse and no currently accepted medical use.

Both GBL and GHB can produce sedative and hypnotic effects when consumed, but they can have different potencies and duration of action. GHB is generally considered to be more potent than GBL, and it can have a longer duration of action. This means that a smaller dose of GHB is needed to produce the desired effects, and the effects may last longer than with GBL.

There are also differences in the routes of administration for GBL and GHB. Both substances can be consumed orally, but GBL can also be converted to GHB by the body when ingested. GHB can also be administered intravenously or intramuscularly, which can increase the risk of overdose and other adverse effects

In terms of medical uses, GHB has been approved for use in some countries as a treatment for narcolepsy and alcohol dependence. It is believed to help reduce the severity of narcolepsy symptoms, such as excessive daytime sleepiness and cataplexy, and may also help reduce alcohol cravings and withdrawal symptoms. GBL, on the other hand, has no approved medical use and is not recommended for use in any medical setting.

Both GBL and GHB can have potentially harmful side effects, including dizziness, drowsiness, confusion, nausea, vomiting, loss of consciousness, respiratory depression, and coma. They can also be addictive and can lead to physical dependence with chronic use. GBL and GHB can also interact with certain medications and can cause dangerous side effects when taken with certain drugs, such as alcohol and benzodiazepines.

In conclusion, GBL and GHB are both gamma hydroxybutyrate compounds that can produce similar sedative and hypnotic effects when consumed. However, there are some key differences between the two substances, including their chemical structures, legal status, potency and duration of action, routes of administration, and potential risks and side effects. GBL and GHB should be used with caution and are not recommended for recreational use due to the potential for harmful side effects and addiction.

Gamma Hydroxybutyrate

Where can i buy Gamma Butyrolactone (GBL) & Gamma Hydroxybutyrate (GHB) Online

It is illegal to possess, sell, or manufacture GBL and GHB in many countries, including the United States. These substances are controlled substances and are not available for purchase through legitimate channels. In the United States, it is a federal crime to possess, distribute, or manufacture these substances, and penalties can include fines and imprisonment.

It is not recommended to try to purchase GBL or GHB online or from any other illegal source. The substances that are sold as GBL or GHB on the internet or through other illegal channels may not be pure or may be mixed with other dangerous substances. Using these substances can be extremely hazardous and can lead to serious health consequences, including overdose and death.

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